In collaboration with Ichor Therapeutics, we've launched a new pilot study, in order to devise extraction and quality control methods of the bovine pineal gland extract epithalamin, as described in Dilman et al.
In mouse and rat studies, epithalamin showed even larger effects on lifespan than the synthetic peptide epitalon, as well as increasing pineal synthesis of serotonin, N-acetylserotonin, and melatonin, so it seems worth running lifespan studies for epithalamin as well as epitalon, once appropriate manufacturing protocols for epithalamin can be devised.
Dilman, V. M., et al. "Increase in lifespan of rats following polypeptide pineal extract treatment." Experimentelle Pathologie 17.9 (1979): 539-545.